DimLift: Interactive Hierarchical Data Exploration through Dimensional Bundling

The identification of interesting patterns and relationships is essential to exploratory data analysis. This becomes increasingly difficult in high dimensional datasets. While dimensionality reduction techniques can be utilized to reduce the analysis space, these may unintentionally bury key dimensions within a larger grouping and obfuscate meaningful patterns. With this work we introduce DimLift , a novel visual analysis method for creating and interacting with dimensional bundles . Generated through an iterative dimensionality reduction or user-driven approach, dimensional bundles are expressive groups of dimensions that contribute similarly to the variance of a dataset. Interactive exploration and reconstruction methods via a layered parallel coordinates plot allow users to lift interesting and subtle relationships to the surface, even in complex scenarios of missing and mixed data types. We exemplify the power of this technique in an expert case study on clinical cohort data alongside two additional case examples from nutrition and ecology.acceptedVersio

Interactive Visual Analysis of Heterogeneous Cohort Study Data

Cohort studies in medicine are conducted to enable the study of medical hypotheses in large samples. Often, a large amount of heterogeneous data is acquired from many subjects. The analysis is usually hypothesis-driven, i.e., a specific subset of such data is studied to confirm or reject specific hypotheses. In this paper, we demonstrate how we enable the interactive visual exploration and analysis of such data, helping with the generation of new hypotheses and contributing to the process of validating them. We propose a data-cube based model which handles partially overlapping data subsets during the interactive visualization. This model enables seamless integration of the heterogeneous data, as well as linking spatial and non-spatial views on these data. We implemented this model in an application prototype, and used it to analyze data acquired in the context of a cohort study on cognitive aging. We present case-study analyses of selected aspects of brain connectivity by using the prototype implementation of the presented model, to demonstrate its potential and flexibility

NFDI-Neuro: building a community for neuroscience research data management in Germany

Increasing complexity and volume of research data pose increasing challenges for scientists to manage their data efficiently. At the same time, availability and reuse of research data are becoming more and more important in modern science. The German government has established an initiative to develop research data management (RDM) and to increase accessibility and reusability of research data at the national level, the Nationale Forschungsdateninfrastruktur (NFDI). The NFDI Neuroscience (NFDI-Neuro) consortium aims to represent the neuroscience community in this initiative. Here, we review the needs and challenges in RDM faced by researchers as well as existing and emerging solutions and benefits, and how the NFDI in general and NFDI-Neuro specifically can support a process for making these solutions better available to researchers. To ensure development of sustainable research data management practices, both technical solutions and engagement of the scientific community are essential. NFDI-Neuro is therefore focusing on community building just as much as on improving the accessibility of technical solutions

Obtaining Patient-Reported Outcomes Electronically With “OncoFunction” in Head and Neck Cancer Patients During Aftercare

The disease and treatment of patients with head and neck cancer can lead to multiple late and long-term sequelae. Especially pain, psychosocial problems, and voice issues can have a high impact on patients’ health-related quality of life. The aim was to show the feasibility of implementing an electronic Patient-Reported Outcome Measure (PROM) in patients with head and neck cancer (HNC). Driven by our department’s intention to assess Patient-Reported Outcomes (PRO) based on the International Classification of Functioning during tumor aftercare, the program “OncoFunction” has been implemented and continuously refined in everyday practice. The new version of “OncoFunction” was evaluated by 20 head and neck surgeons and radiation oncologists in an interview. From 7/2013 until 7/2017, 846 patients completed the PROM during 2,833 of 3,610 total visits (78.5%). The latest software version implemented newly developed add-ins and increased the already high approval ratings in the evaluation as the number of errors and the time required decreased (6 vs. 0 errors, 1.35 vs. 0.95 min; p<0.01). Notably, patients had different requests using PRO in homecare use. An additional examination shows that only 59% of HNC patients use the world wide web. Using OncoFunction for online-recording and interpretation of PROM improved data acquisition in daily HNC patients’ follow-up. An accessory timeline grants access to former consultations and their visualization supported and simplified structured examinations. This provides an easy-to-use representation of the patient’s functional outcome supporting comprehensive aftercare, considering all aspects of the patient’s life

3D Visualization of Vasculature: An Overview

Summary. A large variety of techniques has been developed to visualize vascular structures. These techniques differ in the necessary preprocessing effort, in the computational effort to create the visualizations, in the accuracy with respect to the underlying image data and in the visual quality of the result. In this overview, we compare 3D visualization methods and discuss their applicability for diagnosis, therapy planning and educational purposes. We consider direct volume rendering as well as surface rendering. In particular, we distinguish model-based approaches, which rely on model assumptions to create “idealized ” easy-to-interpret visualizations and model-free approaches, which represent the data more faithfully. Furthermore, we discuss interaction techniques to explore vascular structures and illustrative techniques which map additional information on a vascular tree, such as the distance to a tumor. Finally, navigation within vascular trees (virtual angioscopy) is discussed. Despite the diversity and number of existing methods, there is still a demand for future research which is also discussed.

Intuitive mapping of perfusion parameters to glyph shape

Abstract. Perfusion data characterize the regional blood flow in human tissue. For each voxel, a time-intensity curve (TIC) represents the enhancement of a contrast agent (CA). Parameters describing the TIC shape, e.g. the area below the curve (1), maximum (2), and slope (3), characterize the perfusion and have to be derived and integrated for diagnosis. We present the integrated visualization of perfusion parameters based on their intuitive mapping to glyph shape. Glyph attributes such as size, vertical extension and orientation are modified according to (1), (2), and (3) respectively, thereby generating an easy to interpret coding of TIC shape. We further introduce a multi-resolution glyph display and couple our visualizations with a feature specification component.

Survey of Glyph-based Visualization Techniques for Spatial Multivariate Medical Data

In this survey article, we review glyph-based visualization techniques, which have been exploited when visualizing spatial multivariate medical data. To classify these techniques, we derive a taxonomy of glyph properties, which is based on classification concepts established in information visualization. By considering both the glyph visualization as well as the interaction techniques that are employed to generate or explore the glyph visualization, we are able to classify glyph techniques into two main groups: those supporting pre-attentive and those supporting attentive processing. With respect to this classification, we review glyph-based techniques described in the medical visualization literature. Based on the outcome of the literature review, we propose design guidelines for glyph visualizations in the medical domain